Topliss Tree for Aromatic Substitutions

The Topliss tree is a simple stepwise process for phenyl group optimization. By making a few compounds sequentially following the Topliss tree, you can quickly identify a more potent tool compound for use in protein co-crystallization or a functional assay. The preliminary SAR this generates also helps prioritize your many hits and identify which compounds have no rational SAR and are likely just assay interference compounds. This poster has a partly glossy, partly matte finish..

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• 10 mil (0.25 mm) thick
• Slightly glossy
• Fingerprint resistant


This product is made especially for you as soon as you place an order, which is why it takes us a bit longer to deliver it to you. Making products on demand instead of in bulk helps reduce overproduction, so thank you for making thoughtful purchasing decisions!